Myeloid-derived suppressor cells regulate T cell and B cell responses during autoimmune disease
نویسندگان
چکیده
منابع مشابه
Myeloid-derived suppressor cells regulate T cell and B cell responses during autoimmune disease.
MDSCs are a heterogeneous group of myeloid cells that suppress T cell activity in cancer and autoimmune disease. The effect of MDSCs on B cell function is not clear. Using the CIA model of autoimmune disease, we found an increase in M-MDSCs in the periphery of WT mice with CIA compared with naïve mice. These MDSCs were absent from the periphery of CCR2(-/-) mice that developed exacerbated disea...
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ژورنال
عنوان ژورنال: Journal of Leukocyte Biology
سال: 2015
ISSN: 0741-5400
DOI: 10.1189/jlb.4a0314-139r